Cancer risk estimates for a year old with a pathogenic variant

Management Recommendations

Graffeo R, Livraghi L, Pagani O, Goldhirsch A, Partridge AH, Garber JE. Time to incorporate germline multigene panel testing into breast and ovarian cancer patient care. Breast Cancer Research and Treatment. 2016 Dec;160(3):393-410.   Tung N, Domchek SM, Stadler Z, Nathanson KL, Couch F, Garber JE, Robson ME. Counselling framework for moderate-penetrance cancer-susceptibility mutations. Nature Reviews Clinical Oncology. 2016 Sep;13(9):581-8.   National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology:Breast and Ovarian.   National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: Colorectal.   Paluch SS, Cardoso F, Sessa C, Balmana J, Cardoso MJ, Gilbert F, Senkus E. Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening. Annals of Oncology. 2016; 27(5), 103-110. Graffeo R, Livraghi L, Pagani O, Goldhirsch A, Partridge AH, Garber JE. Time to incorporate germline multigene panel testing into breast and ovarian cancer patient care. Breast Cancer Research and Treatment. 2016 Dec;160(3):393-410.   Tung N, Domchek SM, Stadler Z, Nathanson KL, Couch F, Garber JE, Robson ME. Counselling framework for moderate-penetrance cancer-susceptibility mutations. Nature Reviews Clinical Oncology. 2016 Sep;13(9):581-8.   National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology:Breast and Ovarian.   National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology:Colorectal.   Paluch SS, Cardoso F, Sessa C, Balmana J, Cardoso MJ, Gilbert F, Senkus E. Prevention and screening in BRCA mutation carriers and other breast/ovarian hereditary cancer syndromes: ESMO Clinical Practice Guidelines for cancer prevention and screening. Annals of Oncology. 2016; 27(5), 103-110.

Bibliography for

If you want more information about classification of a specific variant in the gene, you can search for the latest variant information at ClinVar.

The estimates on this website are based on extensive literature review identifying reliable studies on the cancer risk implications for each gene. We welcome any questions or comments to keep our website up-to-date. To post your suggestions, click here.

Computations are provided by the Risk Web Service developed jointly by the Hughes Lab at the Massachusetts General Hospital and the Bayes Mendel Lab at the Dana-Farber Cancer Institute.

The use of this report is subject to the terms and conditions stated on https://www.ask2me.org.

If you want more information about classification of a specific variant in the gene, you can search for the latest variant information at ClinVar or Varsome.

The estimates on this website are based on extensive literature review identifying reliable studies on the cancer risk implications for each gene. We welcome any questions or comments to keep our website up-to-date.

Computations are provided by the Risk Web Service developed jointly by the Hughes Lab at the Massachusetts General Hospital and the Bayes Mendel Lab at the Dana-Farber Cancer Institute.

The use of this report is subject to the terms and conditions stated on https://www.ask2me.org.

 

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